leaf extract diet has a preventive effect against an STZ-induced
diabetic phenomenon in rats[16]. Recently, mulberry juice has been
shown to have the ability to reduce elevated plasma levels of lipid
peroxide in mice loaded with water immersion restraint stress[17].
Active compounds have been separated from the mulberries that have
antidiabetic properties [18]. Furthermore, anthocyanin-rich fruits
have been described that show memory improvement efficacy in
animal models [19]. Importantly, mulberry leaf extracts prevents
amyloid fibril formation and shows neuroprotective effects [20].
However, the suppressive or preventive effects of mulberry on ageassociated deficits in memory and the antioxidant capacity of
mulberries have not yet been discussed in SAMP8 mice.