When antibiotics were invented, the cure became available. If scientists had been working with a different principle of inquiry, they might have noticed that most victims of tuberculosis were poor, and lived in crowded conditions, and had poor diets. If the focus of science at the time had been determined to be these factors. Tuberculosis in England was in decline before the invention of antibiotics; this was because there were less poor people in England, and living conditions were better.
If you are teacher who has inquiry as a philosophy, you will value the different perspectives that your students bring to a question. You might set out a topic worthy of exploration, but you will leave much else up to your students. You can even leave the topic open if you encourage your students to do independent research projects beyond the curricular material being covered in class.