International Care Ethics Observatory News
The International Care Ethics (ICE) Observatory is based in the School of Health Sciences, Faculty of
Health and Medical Sciences at the University of Surrey, Guildford, United Kingdom.
The overall aim of the ICE Observatory is to engage in research and scholarship that illuminate the
importance and complexity of care activities and underpin innovative and effective interventions that
develop and sustain ethical care practices. The ICE Observatory acts as an interdisciplinary, national and
international hub of educational, organisational and research expertise and activity to revalue care and promote
an in-depth understanding of, and commitment to, ethics in health and social care. In addition to initiating
and promoting international research, the Centre also hosts an annual conference, regular ethics
seminars and a post-graduate professional ethics summer school.
Go to: http://www.surrey.ac.uk/fhms/research/centres/ICE/route of administration, concurrent benzodiazepines, nor ingestion of ETOH were associated with significant decreases in systolic BP or heart rate (P = ns for all comparisons). Decreases in oxygen saturations, however, were significantly larger in ETOH+ patients who received IM olanzapine or IM olanzapine + benzodiazepines. Route of administration, concurrent benzodiazepines, nor ingestion of ETOH was associated with significant decreases in systolic blood pressure or heart rate (p = ns for all comparisons). Decreases in oxygen saturations, however, were significantly larger in ETOH+ patients who received IM olanzapine or IM olanzapine + benzodiazepines. Conclusions: Oral olanzapine was not associated with significant vital sign changes in ED patients. Intramuscular olanzapine also was not associated with vital sign changes in ETOH− patients. In ETOH+ patients, IM olanzapine was associated with significant oxygen desaturations. In ETOH+ ED patients, oral olanzapine (with or without benzodiazepines) or haloperidol may be safer choices. ETOH+ patients may have differential effects with the use of IM SGAs such as olanzapine and should be studied separately in drug trials.
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