Gymnema montanum Hook., a member of the family Asclepiadaceae,
is a rare, endangered, and endemic plant species found
mainly in Western Ghats, India.1 Further, we are not aware of
any studies that have been done on G. montanum. There are reports
that some Gymnema species (G. sylvestre, G. inodorum, and
G. yunnanese) help to repair or regenerate the pancreatic -cells,
which play a crucial role in the production and secretion of
insulin.2–4 In recent years, for various reasons, the popularity of
complementary medicine has increased. Dietary measures and
traditional plant therapies as prescribed by ayurvedic and other
indigenous systems of medicine are used commonly in India.5 In
recent times many traditionally used medicinal plants have been
tested for their antidiabetic potential by various investigators in
experimental animals.6
Oxidative stress plays an important role in chronic complications
of diabetes and is postulated to be associated with increased
lipid peroxidation.7 Under physiologic conditions, a wide range of
antioxidant defenses protects the body against the adverse effects
of free radical production in vivo.8 The elevated levels of blood
glucose in diabetes produce oxygen free radicals that cause membrane
damage due to peroxidation of membrane lipids and protein
Gymnema montanum Hook., a member of the family Asclepiadaceae,is a rare, endangered, and endemic plant species foundmainly in Western Ghats, India.1 Further, we are not aware ofany studies that have been done on G. montanum. There are reportsthat some Gymnema species (G. sylvestre, G. inodorum, andG. yunnanese) help to repair or regenerate the pancreatic -cells,which play a crucial role in the production and secretion ofinsulin.2–4 In recent years, for various reasons, the popularity ofcomplementary medicine has increased. Dietary measures andtraditional plant therapies as prescribed by ayurvedic and otherindigenous systems of medicine are used commonly in India.5 Inrecent times many traditionally used medicinal plants have beentested for their antidiabetic potential by various investigators inexperimental animals.6Oxidative stress plays an important role in chronic complicationsof diabetes and is postulated to be associated with increasedlipid peroxidation.7 Under physiologic conditions, a wide range ofantioxidant defenses protects the body against the adverse effectsof free radical production in vivo.8 The elevated levels of bloodglucose in diabetes produce oxygen free radicals that cause membranedamage due to peroxidation of membrane lipids and protein
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