Music rings in as the camera follows Spider-Man falling to earth. A stunning sequence follows Spider-Man playing webbing his way through the city. He overhears a helicopter radio announcing a plutonium shipment under siege at Oscorp. Spidey swings into action to help. A big tow truck is being driven by a bald guy with a Russian accent (Paul Giamatti). He's bashing lots of Manhattan vehicles as he tows/steals the Oscorp truck. Armed assistants set explosives to blow the hatch as the Russian rolls over police cars. Spidey swings impressively through buildings in hot pursuit.
The goons (Dusan Hyska & Andrei Runtso) blow the hatch and hop into the van. There's a container of yellowish vials that are their target. Spidey hops onto the tow truck and engages in some Spidey banter with the Russian (who clearly has no idea who he is). As the goons prepare to hijack the plutonium, we cut to a Oscorp employee the socially inept geek Max Dillion (Jamie Foxx) stumbling through a crowd with an armful of blueprints. Naturally, the prints get knocked from his hands and roll into the street JUST as Spidey and the Russian barrel around the corner. Spidey leaps to the rescue and prevents Max from being squashed by a cab. Spidey hands him the plans and notes that he works at Oscorp before leaping away.