Sherlock Holmes: He is one of the best experts in Europe and a well-known detective. He stays relatively in the background, but ultimately solves the mystery with his logic, observation, and deduction skills. He is sneaky and doesn’t even let his close friends or the people he endangers know his plan fully.
Dr. Watson: He is Sherlock Holmes’ sidekick and the narrator of the story. He is a retired military doctor. He is a true friend of Holmes and puts a great deal of faith in him. He doesn’t always pick up on everything, but he does help Holmes out. He is the one that investigates while Holmes is busy.
Dr. Mortimer: He is a young and popular country doctor that is recently retired from Charing Cross Hospital. He is the person that brings the case to Sherlock Holmes. He and Sir Charles were close friends and lived near each other. He is a kind man that is worried about the new heir.
Mr. Jack Stapleton: He is a scheming and abusive man. He abused his wife, who he made everyone believe was his sister for his own purposes, mentally and physically. He also changed his name and got close to the heirs and friends of the Baskervilles after finding out there were two remaining that prevented him from receiving the estate. He is very intelligent; he set up a school, he was a naturalist, he killed Sir Charles by frightening him, he used people, he was able to keep the hound unknown, and he would have gotten away with it all if Sherlock Holmes was not on the case. He was the bad guy and died in the moorland trying to run away.
Miss Beryl Stapleton: She is Jack Stapleton's wife, but she poses as his sister. She was used and abused by her husband. She said she could take the abuse as long as he loved her, but she was just a useful tool to him. She isn’t completely the bad guy, though. She doesn’t stop Jack, but she does try warning Sir Henry.
Sir Charles Baskerville: He was a superstitious old man that “died of fright.” He had a bad heart. He was generous to people and too trusting.
Sir Henry Baskerville: He is Sir Charles’s nephew and closest living relative, making him the heir to the Baskerville estate. He seems to be more logical than his uncle and not as superstitious. He is determined to go to the estate even though there is the curse. He is kind to the Barrymore's after he finds out their secret. He has faith in Holmes and trusts him.
Sir Hugo Baskerville: He is the first Baskerville to fall prey to the curse. He was a drunkard, vile, and godless. He was an ancestor of the Baskervilles and was brutally murdered by a hound out on the moor.
Laura Lyons: She was the daughter of Mr. Frankland. She was disowned and abandoned. She looked to Stapleton and Sir Charles for help. She was supposed to meet Sir Charles at the time he died, but she never showed. She was another tool used by Stapleton.
Lestrade: She was a police inspector for Scotland Yard.
Cartwright: He was the boy who ran the errands for Sherlock Holmes.
Mr. Frankland: He was Laura Lyons father. He was nosey and in everyone’s business.
The Convict: He was the murderer and brother of Mrs. Barrymore. He is used to getting his way and uses his sister.
Mr. and Mrs. Barrymore: They were close friends and the help of Sir Charles. They are kind people.