In this study, all strains of
lactobacilli and bifidobacteria were able to produce lactic
acid at total concentrations ranging from 3.50 to 4.75 mg/mL.
Beneficial effects of lactic acid on skin such as improving skin
barrier function, hydration and lightening have been extensively reported. It is also reported that topical application of
lactic acid at low concentrations of 0.1–1 % could exhibit
antibacterial activity against most dermal pathogenic bacteria
(Pasricha et al. 1979). Our current study also showed that
strains of lactobacilli and bifidobacteria were able to produce
acetic acid at total concentrations ranging from 1.84 to
3.32 mg/mL. Nagoba et al. (2008) reported that topical application of acetic acid at a low concentration of 0.5 % successfully eliminated Pseudomonas aeruginosa from burns and
soft tissue wounds of 14 out of 16 patients within 2 week