When we take a historical perspective of antipsychotics, there are really 2 waves of antipsychotics. The first series of breakthroughs started in the 1950s with chlorpromazine (Thorazine) and ended with the high-potency conventional antipsychotics. And then there was the development and rapid introduction of the newer or so-called atypical antipsychotics over the last 10 years between clozapine and ziprasidone. So we have 2 classes of agents, the older conventionals and the newer atypicals.