In AT, the release of AA can be catalyzed by AdPLA or by other
types of PLA2 released from macrophages[9]. AdPLA is highly and
exclusively expressed in AT and is associated with adipocyte
differentiation and lipolysis [39]. Ablation of AdPLA in mice caused
a reduction in triglyceride levels and insulin resistance in response to
a HF diet [9,39,40].