2. Methods and materials
2.1. Subjects
This study was approved by the Appalachian State University Institutional Review Board. Twenty-five postmenopausal women and men aged 18 to 50 years were recruited and randomized to BB (n, 13) or placebo (PL) groups (n, 12). Furthermore, subjects identified as prehypertensive (≥120/80 mm Hg) were examined as a subset to investigate the effects of supplementation. It should be noted that this subset analysis was decided upon after the study concluded. Participants were nonmedicated (prescription or over the counter) and free from any other disease or cardiovascular complication. Participants were not involved in a formal exercise training program or on vitamin-mineral supplements exceeding 100% of the Dietary Reference Intake standards.