Analytical chemistry is playing an ever-increasingly important role in the global wine industry. Chemical
analysis of wine is essential in ensuring product safety and conformity to regulatory laws governing the
international market, as well as understanding the fundamental aspects of grape and wine production to
improve manufacturing processes. Within this field, advanced instrumental analysis methods have been
exploited more extensively in recent years. Important advances in instrumental analytical techniques
have also found application in the wine industry. This review aims to highlight the most important
developments in the field of instrumental wine and grape analysis in the African context. The focus of this
overview is specifically on the application of advanced instrumental techniques, including spectroscopic
and chromatographic methods. Recent developments in wine and grape analysis and their application in
the African context are highlighted, and future trends are discussed in terms of their potential contribution
to the industry.