markedly inhibited the growth of all the tested
bacteria. Almost all V. cholerae and B. fragilis were destroyed after
1.5 h and 2 h of incubation, respectively, in the presence of 0.1% (w/
v) chito-oligomers in the culture medium. Although, the required
time for killing all S. disenteriaewas 1.5 h and 2.5 h for COS and NAc-
COS respectively, suggesting that COS is a more effective antimicrobial
agent.