Schistosomiasis is a serious public health problem in Brazil and worldwide. Although the drugs used to
treatment schistosomiasis are effective, the disease continues to expand in all endemic countries due to
constant reinfection, poor sanitation, and the lack of effective programs for disease control. However,
advances generated through genome projects have provided important information that has improved
the understanding of the biology of this parasite. These advances, associated with the advent of bioinformatic
analysis, are becoming an important tool in reverse vaccinology.