A 43-year-old woman was referred by her dentist for assessment of asymptomatic palatal pigmentation that was identified approximately three-months following imatinib therapy for chronic myeloid leukemia (CML). No such pigmentation was identified prior to onset of therapy. She was otherwise healthy and did not smoke cigarettes. There was no history of palatal trauma or chronic irritation. She had used no other medication; medications associated with oral melanosis were specifically denied. Hyper- or hypo-pigmentation affecting other muco-cutaneous sites was also denied.
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