Bioadhesive-coated niosomal formulation of
acetazolamide prepared from span 60,
cholesterol stearylamine or dicetyl phosphate
exhibits more tendency for reduction of
intraocular pressure as compared to marketed formulation (Dorzolamide) The chitosancoated
niosomal formulation timolol maleate
(0.25%) exhibits more effect for reduction
intraocular pressure as compared to a
marketed formulation with less chance of
cardiovascular side effects48