widely accepted by tasters for tested properties. After cooking rice with heat, Rice Formula 2 (after cooking), had reduced γ-oryzanol, α-tocopherol, total phenol levels and antioxidant activities with statistical significance in every method. Furthermore, a temperature of 38±2°C was found capable of giving rats higher GPx while polyphenol substances from extracts of Rice Formula 2 at 500 mg/kg were found to have the effect of reducing GPx in rats. Based on this study, rice may be indicated as a naturally encountered antioxidant source. Polyphenol substances from rice extracts were found capable of reducing heat-related stress to the red blood cells of rats.