Poppy North, a normal teenage girl, is diagnosed with terminal pancreatic cancer. Her best friend James Rasmussen, secretly a vampire and her soulmate, rushes to find a cure, knowing that less than three percent of patients with pancreatic cancer survive. James decides to turn Poppy into a vampire in order to save her life. After Poppy is turned, James's cousin, Ash, abducts Poppy and takes her to Las Vegas where they attend a party held by the Lord of the Night World so that Ash can turn her in (Poppy is an "illegal" vampire). James manages to save her, and it is revealed that Poppy has every right to know about the Night World because she is actually a "lost" witch, a witch unaware of her magical heritage.James and Poppy set out to find Poppy's father supposing he could help them.