The demographic characteristics were as shown in Table I and the sputum production determined by the history was variable, ranging from 30 to 132 ml per day. Patients had varied amount of sputum, type of sputum and dyspnea grading (MRC classification) as shown in Table II. The comparison of the wet sputum weight and volume measured after conventional and ACBT therapies as shown in Table III suggested no statistically significant difference (p0.751 and 0.630, respectively). The crossover analysis using STATA for the measured value differences of the absolute PFT values also suggested no statistically significant difference between the conventional and ACBTtherapies (Table IV). A statistically significant difference in FEV1/FVC percentage predicted values were noted between pre-and post-therapy in both therapies (Table V). However, no significant difference was seen in FVC and FEV1 values preand post-therapy in either group. As shown in Table VI, the VAS score comparison for comfort showed a statistically significant difference (p0.004) with majority of patients being comfortable in performing ACBT for airway clearance.