The condensation product of allicin, ajoene, which has
a similar oxygenated sulfur group, has been shown to
inhibit the proliferation of Trypanosoma cruzi, possibly by
inhibition of phosphatidylcholine biosynthesis [29].
Ajoene was also recently shown to inhibit phosphatidylcholine
biosynthesis in the human pathogenic fungus
Paracoccidioides brasiliensis [30]. The inhibition capacities
shown for ajoene clearly suggest that additional
microbe-specific enzymes may also be targets for allicin.