Patient non-adherence and difficulties following an effective emollient application regimen are well documented in the dermatology literature (Baker,Rayman, 2008).
A study by Somroo et al (2011) showed an excess of 70% of patients with diabetes possibly non-adherent to a daily moisturising routine.
Many patients feel that multiple daily applications of an emollient contribute to the already significant burden experienced as a result of their disease (Loden et al, 2005).
Locke et al (2012) propose reducing the burden of repeated daily applications by the identification of an emollient that is effective at reducing relevant risk factors for diabetes foot ulceration with a once-daily application, and thus improving patient adherence.