High quality coating is necessarySince the virus damages intestinal cells in the small intestine and in the colon, it is crucial that butyrate is able to reach these areas. Butyrate can only arrive in the lower luminal parts of the intestinal tract when it is protected from metabolisation in the stomach and is gradually released in the distal regions of the intestine. The most efficient way to achieve this is by administering a protected butyrate with precision delivery capacity.This is also done with product used in the trials in this article. Different coated butyrate products are available for use in animal production. They come however in many different shapes and forms. One should make a clear distinction between high quality coatings that result in optimal protection and precision delivery of butyrate as opposed to coatings that are solely applied to cover the distinct butyrate smell. In recent research done at the University of Illinois (Sotak et al., 2013) the importance of a high quality coating was demonstrated. Weanling pigs were randomly allotted to three dietary treatments (six replicate pigs per treatment), namely a control group (no butyrate supplementation), a group receiving 4kg/tonne of a smell coated butyrate (50% Na-butyrate) and a group receiving 4kg/ tonne of a precision-delivery butyrate (butyrate supplement, 30% Na-butyrate). Pigs were euthanized and the concentration of butyrate was analyzed in samples from different parts of the intestinal tract.Weanling pigs fed butyrate supplementation had significantly higher (P<0.05) concentrations of butyrate in the jejunum and ileum in comparison with both the control group and the group fed the smell coated butyrate (Figure 4). It could therefore be concluded that administration of high quality protected butyrate,in spite of lower percentage of Na-butyrate (30 %), was effective in delivering butyrate to the lower intestinal tract of pigs, whereas supplementation of the more concentrated (50 %) but less protected butyrate (smell coated) was not.
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