In a study at Brown University School of Medicine, the intake of AGE lowered cholesterol levels and blood pressure in men with high cholesterol levels, men received AGE at a dose of 800 mg/day, for six months, followed by placebo for four months. Cholesterol levels and blood pressure were measured monthly. Results showed that total cholesterol levels fell by an average of six to seven percent and that systolic blood pressure decreased by 5.5 percent; there was a smaller decrease in diastolic pressure.