the quorum sensing molecules used for communication with other cells or inducing hyphal growth. Anti-quorum sensing activity of LGO has been reported in Vibrio campbellii (Viktorova et al., 2020). The present study suggests that the components present in LGO interrupt important steps in biofilm formation, thereby controlling the biofilm on materials as well as associated infections.The cytotoxic studies on HaCatT keratinocytes cell line showed that a lower concentration of LGO maintained cell viability (Fig. 5). Cells showed 51.5 and 70.5% viability at 1.25 and 0.6 ll/ ml concentrations of LGO respectively. Moderate toxicity was observed with LGO on HaCatT keratinocytes cell lines and higher concentration (5–10 ll/ml) of LGO and decreased the viability of cells below 10%. The IC50 value for LGO on HaCatT keratinocytes cells was approximately 1.26 ll/ml. Similarly, the citral component in LGO showed moderate cytotoxicity (IC50 = 39.48 lg/ml) and the viability of human dermal fibroblast cells was decreased up to 5% viability at 0.25% v/v (Adukwu et al., 2016). Toxicity studies of C. citratus on W138 cells showed moderate toxicity (IC50 = 39.77 lg/ ml) (Kpoviessi et al., 2014). Therefore based on the present study,