INTRODUCTION
In the last decades there has been an increase
in the interest for studying the metabolic syndrome
in psychiatric patients and plenty of evidence about
the relationship exists. There are still many
uncertainties, doubts, and controversies related to
metabolic syndrome and bipolar disorder. Some
researches have very critical opinions who are
trying to challenge metabolic syndrome as an
independent diagnostic entity (Bakker et al. 2007,
Reaven, 2005). On the other hand, it is known that
the timely detection of metabolic syndrome or its
individual components can be of great clinical
significance, especially in some patients with
mental disorders including a bipolar disorder
(Jakovljević 2007, Bakker et al. 2007). In many
psychiatric patients the risk factors, which are an
integral part of metabolic syndrome, are rarely
controlled. They are often underestimated and
insufficiently treated. There is evidence that people
with mental disorders are more likely to suffer
from metabolic syndrome. On the other side,
people who are diagnosed with metabolic
syndrome often suffer from mental disorders.
However, research on the prevalence of metabolic
syndrome in patients with bipolar disorder is still
surprisingly rare.
The aim of this paper is to analyze
comorbidity of bipolar disorder and metabolic
syndrome, and the association of treatment with
antipsychotics and mood stabilizers with metabolic
syndrome, as well as to point out the necessity of
appropriate preventive measures and treatment of
metabolic syndrome in patient with bipolar
disorder.
INTRODUCTIONIn the last decades there has been an increasein the interest for studying the metabolic syndromein psychiatric patients and plenty of evidence aboutthe relationship exists. There are still manyuncertainties, doubts, and controversies related tometabolic syndrome and bipolar disorder. Someresearches have very critical opinions who aretrying to challenge metabolic syndrome as anindependent diagnostic entity (Bakker et al. 2007,Reaven, 2005). On the other hand, it is known thatthe timely detection of metabolic syndrome or itsindividual components can be of great clinicalsignificance, especially in some patients withmental disorders including a bipolar disorder(Jakovljević 2007, Bakker et al. 2007). In manypsychiatric patients the risk factors, which are anintegral part of metabolic syndrome, are rarelycontrolled. They are often underestimated andinsufficiently treated. There is evidence that peoplewith mental disorders are more likely to sufferfrom metabolic syndrome. On the other side,people who are diagnosed with metabolicsyndrome often suffer from mental disorders.However, research on the prevalence of metabolicsyndrome in patients with bipolar disorder is stillsurprisingly rare.The aim of this paper is to analyzecomorbidity of bipolar disorder and metabolicsyndrome, and the association of treatment withantipsychotics and mood stabilizers with metabolicsyndrome, as well as to point out the necessity ofappropriate preventive measures and treatment ofmetabolic syndrome in patient with bipolardisorder.
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