the pCMV-Sport6- HBc, pCMV-Sport6-HBp, pCMV-Sport6-HBs, and pCMV-sport6-HBx plasmids were constructed as reported previously. Their mRNA expression levels in HepG2 cells were confirmed with RT-PCR anaiysis, and HBc protein expression levels in HepG2 cells was confirmed with Western blotting analysis. SP1 and AP-2A cDNA were obtained using PCR and clone into the pCMV-sport6 plasmid