Mulberry fruits have recently been received much attention as potential sources of functional foods due to several biological and pharmacological effects of anthocyanins (Tsuda, Horio, Kitoh, & Osawa, 1999) and flavonoids (Havsteen, 1983; Solimani, 1997; ). We think that research about the isolation and identification of phenolic compounds existed mulberry fruits (especially M-2 and M-4) and determination of their biological activity in vivo must be processed continuously