After winning a televised model-search competition, he became a successful model. For several years, Gandy was the lead male model for Italian designers Dolce & Gabbana who featured him in their campaigns and fashion shows.
In an industry dominated by skinny models, Gandy's muscular build caused some menswear fashion designers to move to a more masculine standard.[5] The increase in his popularity and name recognition resulted in a broad portfolio of magazine covers, editorial photo shoots, interviews and industry awards. He has gone on to participate in fashion-related and personal projects such as writing a blog for British Vogue, writing car reviews for British GQ, mobile app development and charity work.