James Parkinson’s original description of PD stated that the “senses and intellects” were “uninjured” in the disease. But we have known for many years that this is not the case, possibly because with modern treatment, people with PD live much longer than ever before. In the past decade, physicians have developed a keener awareness of nonmotor symptoms of Parkinson’s and their impact on quality of life for people with PD. These symptoms include personality changes such as the development of passivity, difficulty making decisions, loss of motivation, anxiety, depression and bradyphrenia (slowness in thinking). These and other nonmotor symptoms — including such problems as fatigue, sleep disturbances, constipation, bladder disturbances and changes in sensory perception — can become more serious when motor problems of PD are controlled with medications. Fortunately, many of these nonmotor symptoms can respond to treatment.