However, certain phenomenon likecreaming, aggregation (flocculation and coagulation), Ostwald ripening,and coalescence are the major factors responsible for reducing theirstability [105]. Nanoemulsion fabrication can be achieved by employingtwo main tactics i.e. bottom-up and top-down. Bottom-up techniquescomprise self-assembly of molecules through efficient techniques suchas nanoprecipitation, coacervation, inclusion complexation, and supercritical encapsulation.