based on soluble parasite antigens from one or more Babesia species reduce clinical disease in dogs due to B. canis (35, 49). A vaccine to prevent clinical signs of giardiosis and reduce cyst shedding in dogs and cats is commercially available (39). The vaccine was obtained by disrupting axenically cultured Giardia whole trophozoites. At the end of 2004, a vaccine against canine leishmaniosis, caused by Leishmania infantum, was introduced onto the market. The vaccine is based on the fucose mannose ligand (FML) of L. infantum (11). Finally, a sub-unit vaccine that induces maternal immunity in broiler breeders against coccidiosis, and is based on gametocyte antigens of E. maxima, has been developed and marketed (67).