As the level of these materials increased, the received score values significantly decreased in all their quality attributed. Cake samples made from substituted flour with 2.5% watermelon rinds or sharlyn melon peels showed no significant differences in all their sensory properties and were as acceptable as those of control cake sample. Storage of different cake samples for 21 days significantly reduced all their sensory properties. The minimum reduction in sensory properties was observed in cake substituted with flour at 2.5% watermelon rind or sharlyn melon peel powders followed by 5% of sharlyn melon peels then 5% of watermelon rinds while the maximum reduction was shows in control sample. These results revealed that 2.5% substitution of flour with watermelon rind and sharlyn melon peel powder produced an acceptable cake which was not significantly different from the control cake.