Following the dynamic model, several au-thors10-17 have proposed more popular, general and realistic models with results consistent with physiology. The modelling of the glucose-insulin system has become an interesting topic and sev-eral models have been proposed and studied with the purpose of understanding the system better, investigating possible pathways to diabe-tes as well as providing better insulin administra-tion practices. Many models have been pre-sented as described in a survey by Makroglou et al.18 as well as in the review by Boutayeb and Chetouni19 in which most of the models pro-posed existing in literature can be found.