The primary mechanism that relates NAFLD to different diseases is due to the chronic inflammation it triggers. NAFLD’s oxidative stress is an essential component in its pathophysiology and one of the mechanisms by which it can damage different organs and systems. Therefore, it is essential to consider NAFLD as a pathology to be ruled out in inflammatory respiratory pathologies. A decrease in steatosis and liver fibrosis probably improves the symptoms and prognosis of these respiratory pathologies correcting the inflammatory state (Fig. 1).