Gastritis cystica profunda is described as gastric glands covered with normal gastric mucosa that
locate submucosally and form cystic expansion. Its etiology is not clear, but the most important
cause is prior gastric surgery. There is no agreed treatment because of its rarity. A 44-year-old
female patient was admitted to hospital with complaints of abdominal pain and vomiting. We
found a 2-cm mass in the wall of the stomach as a result of investigations. The patient was
operated on with a preliminary diagnosis of gastric cancer. Surgeon performed excision of the
total mass only. Pathological examination of the mass revealed that it was gastritis cystica
profunda. Gastritis cystica profunda is a rare lesion of the stomach, and can be confused with
other gastric pathologies. Preoperative diagnosis is important because it can prevent unnecessary
resections. Gastritis cystica profunda should be kept in mind in the differential diagnosis of gastric
submucosal masses.