This study demonstrated the fabrication of an SF TE scaffold with 3D interconnected macro-features by indirect AM technology for the facilitation of cellular-based mass transports. The micro-pores within the constructs served as biological cues to promote cell attachment and maintain cell morphology and function by the interactions of chondrocytes and SF. The pre-defined macro-channels facilitate cell migration towards the central regions of the scaffold and the effective mass transportation of nutrients and metabolic waste. The fine structural analysis of the 3D SF constructs revealed that the intrinsic properties, such as the thermal characteristics and chemical structure of SF, were preserved. Finally, the SF scaffolds have been proven as suitable substrates for cell proliferation and the expression of cartilage-specific ECM.