Results: The growth of all isolates (n = 85) from 34 patients was inhibited by 6% NaCl solution. A 10% concentration had a
bactericidal activity on 90% of the isolates. Mucoid and multidrug resistant (MDR) isolates displayed lower MICs compared
to non-mucoid and to non-MDR isolates, respectively. Time-kill kinetics showed that NaCl exhibited a rapid, dose and
growth phase dependent bactericidal effect. Three percent or more of NaCl inhibited biofilm formation for 69% of strongly
adherent isolates. A dose-dependent decrease of preformed biofilm viability and an inhibitory activity on bacterial motility
were observed