Obesity is a complex and difficult disorder which is multi-factorial in its etiology. Central adipose tissue is known to produce adiponectin, which plays a role in the glucose/insulin axis as well as the production of inflammatory cytokines. When central adipose tissue expands through increased fat deposition, it appears that there is a concomitant drop in the production of adiponectin along with a rise in the expression of inflammatory cytokines and C-reactive protein (CRP) [1]. Inflammation is emerging as a predictor of cardiovascular disease and may be considered a precursor of metabolic syndrome. Therefore the ability to reduce inflammation (as measured by CRP) in overweight and obese individuals may be valuable in preventing the progression to diabetes [2,3] and heart disease [4-10]. Inflammation has also been implicated in lung disease [11-13], diseases of the digestive tract [14], skin diseases [15-18], and arthritis [19-24].