The literature review was performed by searching the elec- tronic database PubMed and for relevant studies published between January 2003 and March 2014 (lasting 10 years) and written in English. The methodological quality of each study was assessed, and best-evidence synthesis was applied to draw conclusions about the evidence for the effectiveness of each outcome.
The search terms were shift work, cortisol, insulin resis- tance, diabetes, obesity, and metabolic disorders (Table 1). Mostly included studies were with humans; however, others that had shown relevant conclusions regarding metabolic processes were included as well. Reviews were excluded from our results. Nevertheless, some reviews were used to support theories of the mechanisms involved in the misalignment’s physiological changes in the discussion. To achieve the objective of the present paper, we mainly choose articles that have presented a rationale regarding metabolic disorders and endocrine system.
The literature review was performed by searching the elec- tronic database PubMed and for relevant studies published between January 2003 and March 2014 (lasting 10 years) and written in English. The methodological quality of each study was assessed, and best-evidence synthesis was applied to draw conclusions about the evidence for the effectiveness of each outcome.The search terms were shift work, cortisol, insulin resis- tance, diabetes, obesity, and metabolic disorders (Table 1). Mostly included studies were with humans; however, others that had shown relevant conclusions regarding metabolic processes were included as well. Reviews were excluded from our results. Nevertheless, some reviews were used to support theories of the mechanisms involved in the misalignment’s physiological changes in the discussion. To achieve the objective of the present paper, we mainly choose articles that have presented a rationale regarding metabolic disorders and endocrine system.
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