In the present studies, all the three metallic compounds viz.Hg(II), As(III) and Cu(II) registered a significant decrease in MI vis-a-vis negative control (group I) even against sublethal exposures for shortest exposure period of 24 h. Moreover, even lesser RMI than positive control (group II) coupled with elevated frequencies of CA for above said compounds form a valid ground for potentially cytotoxic nature of these metallic compounds.