In summary, these data lead us to speculate that,besides an involvement in the repair of DNA double strand breaks as observed for BACH1, this novel subfamily of mammalian helicases may be a potential candidate for the response also to UV-induced damage and, thus, may function in the processing of lesions induced by different genotoxic agents.
SUVi/BACH1 may have important role in resolving aberrant DNA structures that are formed during DNA replication of normal and damaged DNA.