The application of single-case research design (SCRD) offers counseling practitioners and researchers a practical and viable method for evaluating the effectiveness of interventions that target behavior, emotions, personal characteristics, and other counseling-related constructs of interest. This article discusses general issues relevant to SCRD, as well as obstacles to its implementation in counseling settings. Steps to SCRD development, application, and analysis that are specific to the counseling field are also provided to encourage its use among counselors and researchers.