In the study,few herbal extracts have shown potent inhibition of ROCK-II activity which supports their role as aphrodisiacs,as claimed in traditional literature.The aphrodisiac activity of those extracts which did not show significant inhibition in ROCK-II assay cannot be ruled out as they might be acting through some other mechanisms(different target site).The study highlighted the vast potential of Indian traditional medicine,which can possibly be harvested for the treatment of erectile dysfunction.These preliminary results from in vitro ROCK-II inhibition can be seen as the groundwork for further studies on isolation and identification of compounds from potent plants and elucidation of their mechanism of action.