who did not find any aluminumeffects on the acquisition in the Morris water maze.The deterioration in learning and memory functions in passiveavoidance task after aluminum treatment recorded in the presentstudy could be due to aluminum-induced neurotoxicity becauseof its ability to promote ROS formation and to enhance free rad-icals generation as well as its reported pro-oxidant activity. Italso increases oxidative stress and lipid peroxidation which couldextensively cause oxidative and degenerative damage of neurons