FIG. 1. the cslA gene and comparison of its product with related proteins. (A) Alignment of the highly conserved U1,U2,U3,andU4 regions in the central cytoplasmid loop predicted S.coelicolor cellulose synthase-like protein with cellulose synthase protein sequences from Agrobacterium tumefaciens (CelAat; NP_533806), S.enterica serovar Typhimurium (BcsA; CAC86199),and Dictyostelium discoideum (DcsA;AAF00200). The D,D,and D35 QXXRW motif ; KAG motif; and QTP motif are indicated by asterisks,colons ,and dots respectively. The dashed line between the first and second blocks indicates that some regions that do not contain conserved motifs are omitted .(B) The csl genes in S.coelicolor. Compared with the operon of S.enterica Typhimurium/E.coli,Streptomyces does not have the bcsB genes also exist in S.avermitilis.