Methods
The method has previously been described in detail [5,6].
In short, the 16 patients, all with BMI>30 kg/m2, free of
thyroid cardiac and renal disease – were advised to follow
a diet containing initially 1800 kcal for men and 1600
kcal for women. The proportions of carbohydrates, fat
and protein were 20%, 50% and 30% respectively. The
daily quantity of carbohydrates was 80–90 g. The recom-
mended carbohydrate consumption was limited to vege-