Discussion
These findings suggest that some fruit, fruit varieties,
and some part of the fruit contain different concentrations
of glycation activity inhibitors. Pomegranate, sudachi and
mangosteen strongly inhibited HSA and collagen glycation; the
apple varieties” alps otome”, “sekai ichi”, and “san jonagold”,
showed higher anti-glycation activity than other varieties in
both glycation models. We have to pay attention to the fact
that the in vitro experimental results are different from the in
vivo reaction. However, these in vitro glycation models are
useful for screening the anti-glycation ingredients from natural
compounds as previously reported 22-24).