QC1 smallest fragment size (bp) Figure 4 Pearson correlation of Qci fragment size and total variants The scatter plot of QCI smallest fragment size vs. number of total variant calls is shown. The red dots represent the extra cohort, while the blue dots represent main cohort samples who share the same geographic background as the extra cohort. The gray line is the best-fit line (Pearson correlation; R 0.61; P 0.001). The extra cohort has QCI smallest fragment size less than 80 bp showing large deviation in number of total variants.