[0031] Other ingredients>
Aside from the active ingredients described above, known additives may be incorporated in the compositions of the present การประดิษฐ์. Although the applicable additives are not particularly limited, those which are commonly used for oral ingestion are preferred and examples that can be used include excipients, binders, disintegrants, lubricants, antiseptics, flavoring agents, aroma corrigents, coloring agents, scents, etc. and any ingredients can be used that are known to have skin improving effects.
[0032] In the compositions of the present การประดิษฐ์, other beautifying or health promoting components that are known to have skin improving effects can be incorporated in combination with the active ingredients. The components that can be used in combination with the active ingredients are not particularly limited and examples include ceramides, lactobacilli, vitamins (e.g. vitamin C), minerals (e.g. calcium), plant extracts, etc.
[0033] Further in addition, components that are exemplified below which are known to
have a ไฟโบรบลาสต์ การเพิ่มจำนวน promoting action, a collagen production promoting action, and an anti-skin aging action may be incorporated in the compositions of the การประดิษฐ์นี้. [0034]
The composition of the การประดิษฐ์นี้ is ที่ควรใช้คือ an oral composition. The oral composition embraces, but is not limited to, for example, foods and beverages, pharmaceuticals and quasi-drugs, etc.; the oral composition is ที่ควรใช้คือ a food and a beverage, ที่ควรใช้มากกว่าคือ a beverage. Exemplary foods and beverages include health foods,
therapeutic foods, foods for specified health use, dietary supplements, dairy products, soft
r
drinks, powders ready for dissolving just before use, etc; foods and beverages for pets, feeds
for livestock, etc. are also included. Particularlypreferred are powders ready for dissolving just before use. If desired, the powders ready for dissolving just before use may be dissolved in coffee, tea, juice, yoghurt, soup, etc. or mixed in cooked food and then ingested. The powders ready for dissolving just before use are particularly superior in terms of stability during storage and the ease of administration, i.e., they can be ingested after being dissolved in or added to beverages or foods of preference. If desired, the composition of the การประดิษฐ์นี้ can be used in the form of tablets or capsules. Pharmaceuticals and quasi-drugs are ตามปกติ in the form of oral preparations such as granules, tablets, capsules, and liquids/solutions.
[0035] The dosage of the composition of the การประดิษฐ์นี้ can be determined as appropriate depending on the subject's age, body weight, health conditions, etc; the daily intake by a human adult of the composition ตามปกติ ranges from 10 mg to 100,000 mg, ที่ควรใช้คือ from 500 mg to 15,000 mg, and ที่ควรใช้มากกว่าคือ from 3,000 mg to 10,000 mg, and the composition can be ingested or administered either in a single dose or in divided portions. As the collagen peptide need be used in a lower dosage, it has become possible to reduce the required daily intake of the composition.
[0036]
The compositions of the การประดิษฐ์นี้ can be used to prevent or ameliorate symptoms of the skin and they are capable of preventing or ameliorating symptoms of the
skin such as, for example, lowered skin moisture retention and elasticity, reduced skin firmness and gloss, rough skin, wrinkles, and dullness.
[0037] Here it is known that the skin improving effects are exhibited by the action for promoting the การเพิ่มจำนวน of ไฟโบรบลาสต์ found in living tissues, in particular, the dermis tissue of the skin, and for that matter, the associated collagen production promoting action and anti-skin aging action. Therefore, in another embodiment of the present การประดิษฐ์, the composition has the ไฟโบรบลาสต์ การเพิ่มจำนวน promoting action, the collagen production promoting action, or the anti-skin aging action.
[0038] The ไฟโบรบลาสต์ การเพิ่มจำนวน promoting action means the action for promoting the การเพิ่มจำนวน of ไฟโบรบลาสต์ found in living tissues, in particular, the dermis tissue of the skin and it can be evaluated by known methods. The active ingredients capable of the ไฟโบรบลาสต์ การเพิ่มจำนวน promoting action are collagen peptide, elastin peptide and โปรทีโอไกลแคน. These ingredients, after being processed into a solid, paste or liquid form, may immediately be applied as a เอเจนต์ปรับปรุงผิว that has the ไฟโบรบลาสต์ การเพิ่มจำนวน promoting action; if desired, the agent may be combined with known additives having the ไฟโบรบลาสต์ การเพิ่มจำนวน promoting action which are included in the agent in the usual manner to formulate a composition. Ingredients that are known to have the ไฟโบรบลาสต์ การเพิ่มจำนวน promoting
action may include, but are not limited to: