The structure ofthe EPS was elucidated by a combination of chemical and ESI-MSas well as NMR (Fig. 1) (Wang, Yang, & Wang, 2013). EPS has been shown to improve the immune responses and antioxidant activity in immunosuppressed mice induced by cyclophosphamide (Jinet al., 2010). However, little is known about the anti-diabetic effectsof EPS. In this study, the hypoglycemic and hypolipidemic effectsof EPS on diabetic KKAy mice was carried out, which would allow abetter understanding of the functional effects about those macro-molecules, and be beneficial to explore new more bioresources.