Patients with early glottal carcinoma are usually treated
with either radiation therapy or transoral laser surgery
(TLS). The choice between these treatments is controversial,
and treatment may vary by geographic region (1). The
current evidence is insufficient to guide management
decisions (2), and a recent systematic review and metaanalysis
failed to identify a single randomized study
comparing TLS with radiation therapy (1). The metaanalysis
suggested that a higher larynx preservation rate
can be achieved with TLS, but owing to the generally
poor quality of the evidence, this result was considered
inconclusive.